Prevalence and factors associated with anastomotic leakage among surgical patients at 2 teaching hospitals in Addis Ababa, Ethiopia

  • Daniel Zemenfes
  • Esayas Tamirat
Keywords: anastomotic leak, risk factors, prevalence, Ethiopia


Background: Gastrointestinal resection and anastomosis is a very common procedure globally. Anastomotic leak is a complication affecting 2% to 10% of patients undergoing gastrointestinal surgery. Different factors have been attributed to the development of leak. This study was designed to assess the prevalence and associated risk factors for anastomotic leak in a period of three years at Tikur Anbessa Specialized Hospital (TASH) and Menilik II Memorial Hospital (MIIMH).

Methods: A retrospective data of 157 patients, for whom intestinal anastomosis was done from 2014 to 2016 at TASH and MIIH, were included in this study. Descriptive statistics were done to assess the prevalence and association of different factors with Anastomotic Leak.

Results: Among the patients operated a total of 17 patients developed postoperative anastomotic leakage, which makes the prevalence rate 10.8%. There was a statistically significant association between emergency presentation, ASA class (≥3) and the need for intraoperative blood transfusion with the occurrence of anastomotic leakage.

Conclusions: The prevalence of anastomotic leakage in this study was 10.8% a bit higher from the usual range (2%-10%). Emergency presentation, those in need of blood transfusion and having higher ASA class were associated with anastomotic leakage.

Original Research