Excisional biopsy and radiotherapy as definitive treatment for ulcerative invasive squamous cell carcinoma of the penis

  • Abubakar S. Muhammad
  • I. Hassan
  • U. Muhammad
Keywords: penile cancer, excisional biopsy, squamous cell carcinoma of penis, groin radiotherapy


Penile cancer is a rare malignancy worldwide with a higher incidence in developing countries. Patients may present early with penile ulcer due to disfigurement, recurrent infections or discomfort. When the lesion is confined to the skin of the root of the penis, excisional biopsy of the ulcer may be a definitive surgical treatment. We present a 67-year-old man with a malignant penile ulcer at the ventral aspect of the root of penis who underwent excisional biopsy with wide margin and closure of the wound defect with a scrotal advancement flap. The histology revealed well-differentiated squamous cell carcinoma with free surgical margin. He developed left inguinal lymphadenopathy which resolved after external beam radiation of the left groin. He defaulted and subsequently developed right groin recurrence after 3 years which was excised and covered with an advancement flap.

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